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Beyond Genetic Engineering

Synthetic biologists are building new organisms.

By Gene Charleton | Thu Nov 05, 2009 01:54 AM ET
synthetic cell

By manipulating the genetic makeup of cells, scientists are able to build new organisms.
National Human Genome Research Institute

Just when you were getting used to the idea of genetic engineering, there’s something new. Listen to the podcast on Engineering Works.

If you’re at all interested in new technology, you probably know that inserting a gene or two into a plant and getting something useful back is no big deal any more. That’s genetic engineering as we now know it.

But listen to this. A new breed of genetic engineers are inventing a new field. They call it synthetic biology. They aim to use the technology pioneered in genetic engineering to build whole new organisms. One new organism these guys are working on is a plant we could harvest and process into petroleum. Not ethanol, like people are talking about to replace gasoline, but good old oil, growing in a field instead of miles underground.

One ambitious group of researchers is aiming eventually at reprogramming trees to grow into the shape of a house instead of leaves and branches. It sounds like science fiction, but they’re serious. We think.

All this will be pretty neat, if it works. But there’s still a long way to go. So far, the longest DNA sequence duplicated in the laboratory is about 35,000 units long. Compare that to human cells that duplicate a sequence three billion, with a B, units long.

Where will it all end? Hard to tell from here. But we’re out of time, and we’re ending here. See you next time.

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