Athletes in 1913 Medically Doped on Caffeine: "In 1917, the 'American Journal of Physiology' published an article with the very descriptive title: 'A comparison of the effects of breakfast, of no breakfast and of caffeine on work in an athlete and a non-athlete,'" writes the Guardian.
We can guess from the title of the study what was being tested, and when reading it the results show that breakfast is good, and caffeine is fine; in small doses. How did they control a "dose" of caffeine? The researchers used Coca-cola syrup. They measured the syrup very specifically so they could easily control the amount of chemical given to each athlete (7oz of cola, with 1.42 grains of caffeine). This was then given in different amounts during different phases of the experiment. The athletes were then tested at their ability to compete.
One un-named athlete failed their test on caffeine while another "reported being irritable and disturbed on high caffeine doses." A high dose for this experiment was 230mg, or between two and three cups of coffee. When not full of stimulant the athletes competed with, "speed, accuracy and control of muscles, and concentration of thought." So, think twice before you enjoy your next cup of legal, addictive stimulant. via The Guardian