Hormone Spritz Makes Fido Friendlier


A potent new spray promotes friendship between animals even, in some cases, if they come from different species, according to a new study.

The spray's active ingredient is oxytocin, which is a naturally occurring hormone released by the pituitary gland. When formulated into a spray, it becomes a veritable Love Potion Number 9, with more emphasis -- at least in this case -- on friendly rather than romantic interactions.

The study, published in the latest issue of the Proceedings of the National Academy of Sciences, looked at how the spray affects dogs, but it holds tremendous promise for human usage too. It might even help to reform curmudgeonly cats.

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It's widely debated whether a dog's level of aggression toward strangers is due to its breed, or the way its owner raises it.

"Studies in humans have already shown that oxytocin affects our tendency to affiliate or cooperate with other people," co-author Miho Nagasawa of the University of Tokyo's Department of Cognitive and Behavioral Sciences told Discovery News.

"As far as we know, there are no studies on cats, but we believe that oxytocin is a hormonal mechanism that facilitates the maintenance of close social bonds not only in dogs or cats, but also in any mammal species since the oxytocin system is very ancient and has similar functions in a wide number of taxa," Nagasawa added.

Lead author Teresa Romero, Nagasawa and their colleagues studied how 16 adult dogs of different breeds behaved both with and without being sprayed by the oxytocin formulation. All of the dogs are pets that live with their owners.

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The scientists recorded any instance of bonding behavior that the dogs showed with other familiar dogs as well as with their owners. The behaviors included sniffing, licking, gentle touching with the nose or paw, playing and resting in contact with the other's body. The researchers also measured how much attention the dogs paid to their owners or to their canine pals.

"We found that after receiving the oxytocin spray, dogs displayed more affiliative behaviors and paid more attention to their owners than during the controls," Romero told Discovery News.

As for how the spray works, the researchers said it significantly changed the dogs' heart rate variability and stimulated secretion of oxytocin. These indicate that the spray "can penetrate into the brain and stimulate the oxytocin system in the central nervous system," Nagasawa said.

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